Staging UICC/AJCC TNM

Primary tumor

Tx Primary tumor cannot be assessed.

T0 No evidence of primary tumor

Tis Carcinoma in situ

T1a Tumor invade lamina propria

Tib tumor invadesmuscle layer

T2 Tumor invades perimuscular connective tissue, no extension beyong serosa or into

liver.

T3 Tumor perforates serosa or directly invades the liver or other adjacent organs or

structure (stomach, duodenum, colon, pancreas, omentum, extrhepatic bile ducrs)

T4 Tumor invades main portal vein or hepatic artery or invades two or more extrahepatic

organs or structures.

Regional Nodes

Nx Regional nodes cannot be assessed

N0 No regional lymph no metastasis

N1 Regional Lymph nodes metastasis

Distant metastasis

Mx distant metastasis cannot be assessed

M0 no distant metastasis

M1 distant metastasis