217. Baseline Flow Cytometry in patients with CLL (Measure 70)

If patient has chronic Lymphocytic leukemia (ICD-9 diagnosis code: 204.10 AND CPT E/M service codes: 99201, 99202, 99203, 99204, 99205, 99212, 99213, 99214, 99215, 99241, 99242, 99243, 99244 and 99245) recommend flow cytometric analysis. Due to the distinct pattern of protein antigens expressed in CLL, flow cytometry should be performed in order to confirm the diagnosis, correctly characterize the pathological cells, and determine prognosis. In some instances, flow cytometry may also offer additional therapeutically relevant information. Flow cytometric studies performed on patients with leukemic cell burden include kappa/lambda to assess clonality. Distinguishing CLL/SLL from mantle cell lymphoma is essential

DESCRIPTION: Percentage of patients aged 18 years and older with a diagnosis of Chronic Lymphocytic Leukemia (CLL) who had baseline flow cytometry studies performed GUIDELINE: If patient has chronic Lymphocytic leukemia, recommend flow cytometric analysis. Due to the distinct pattern of protein antigens expressed in CLL, flow cytometry should be performed in order to confirm the diagnosis, correctly characterize the pathological cells, and determine prognosis. In some instances, flow cytometry may also offer additional therapeutically relevant information. Flow cytometric studies performed on patients with leukemic cell burden include kappa/lambda to assess clonality. Distinguishing CLL/SLL from mantle cell lymphoma is essential.

Reference

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